Norbrook 0.5% Noromectin/Paramectin Pour On For Cattle

• Indicated for the effective treatment and control of the following gastrointestinal roundworms, lungworms, eyeworms, warbles, chorioptic and sarcoptic mange and sucking and biting lice in beef and non-lactating dairy cattle.
• Gastrointestinal roundworms (adults and fourth stage larvae): Ostertagia ostertagi (including inhibited O ostertagi), Haemonchus placei, Trichostrongylus axei, Trichostrongylus colubriformis, Cooperia spp, Oesophagostomum radiatum, Strongyloides papillosus (adult), Trichuris spp (adult).
• Lungworms (adult and fourth stage larvae): Dictyocaulus viviparus.
• Eyeworms (adult): Thelazia spp
• Warbles (parasitic stages): Hypoderma bovis, Hypoderma lineatum.
• Lice: Linognathus vituli, Haematopinus eurysternus, Solenopotes capillatus, Damalinia bovis.
• Mange mites: Chorioptes bovis, Sarcoptes scabiei var bovis.

Dosage: 

• Ivermectin should be administered topically at 500 μg per kg bodyweight (1 ml per 10 kg bodyweight).
• The formulation should be applied along the midline of the back in a narrow strip between the withers and the tailhead.
• To ensure administration of a correct dose, body weight should be determined as accurately as possible; accuracy of the dosing device should be checked.

• Rainfall before or after treatment will not affect the efficacy of Noromectin 0.5% w/v Pour-On Solution.
• Do not apply to areas of skin which have mange, scabs or other lesions or to areas contaminated with mud or manure.
• Formulated for specific use in cattle. It should not be applied or administered to other species, as severe reactions, including fatalities in dogs, may occur.
• Cases of intolerance with fatal outcome are reported in dogs, especially Collies, old English Sheepdogs and related breeds or crosses, and also in turtles/tortoises.” Do not allow these species to come in contact with this product.
• Close container after use.
• Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in effective therapy:
• Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
• Underdosing, which may be due to underestimation of body weight, misadministration of the product, or lack of calibration of the dosing device (if any).
• Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.
• Resistance to ivermectin (an avermectin) has been reported in Cooperia oncophora in cattle within the EU, in Teladorsagia in cattle in developed countries such as New Zealand and Haemonchus in cattle outside the EU. Therefore the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of nematodes and recommendations on how to limit further selection for resistance to anthelmintics.
• As Ivermectin is extremely dangerous to fish and aquatic life, treated animals should not have direct access to surface water and ditches during treatment.
• To avoid secondary reactions due to the death of Hypoderma larvae in the oesophagus or in the spine, it is recommended to administer the product at the end of warble fly activity and before the larvae reach their resting sites.
• It is recommended to treat all animals within a herd or group.
• The shedding of nematode eggs can continue for some time after treatment.
• Undesirable effects are not expected when the product is used at the recommended dose rate.
• Can be administered to beef cows at any stage of pregnancy or lactation.
• Do not combine ivermectin treatment with vaccination against lungworms. If vaccinated animals are to be treated, treatment should not be carried out within a period of 28 days before or after vaccination.
• No signs of toxicity are likely up to 5 mg/kg (10 times the recommended dose rate). There is no known antidote.
• Withdrawal Period: Cattle: Meat: 28 days
• Not to be used in animals producing milk for human consumption.
• Do not use in non-lactating dairy cows including pregnant heifers within 60 days of calving.