Zoetis Cydectin Triclamox Pour On For Cattle

Product Description

Uses:

• Treatment of mixed trematode (fluke) and nematode infections and certain arthropod infestations caused by moxidectin and triclabendazole sensitive strains of:
• Gastro Intestinal Nematodes: Haemonchus placei (adult/L4), Ostertagia ostertagi (adult/L4/inhibited), Trichostrongylus axei (adult/L4), Nematodirus helvetianus (adult/L4), Cooperia oncophora (adult/L4), Cooperia punctata (adult), Oesophagostomum radiatum (adult), Bunostomum phlebotomum (adult).
• Respiratory Tract Nematodes: Dictyocaulus vivparus (adult).
• Liver Fluke: Fasciola hepatica (adult/6-8 week immatures).
• Ectoparasites: Linognathus vituli (adult), Bovicola bovis (adult), Solenopotes capillatus (adult). 
• The product has a persistent effect in preventing re-infection by Ostertagia ostertagi and by Dictyocaulusviviparus for 5 weeks after a single dose.

Dosage: 

• External use only.
• 0.5 mg moxidectin/kg body weight and 20 mg triclabendazole/kg body weight (equivalent to 1 ml of solution for 10 kg) and as a single topical application.
• To be administered directly to the hair and skin along the midline of the back of the animal from the withers to the tail head.
• Apply to clean healthy skin.
• To ensure a correct dosage, body weight should be determined as accurately as possible. Accuracy of the dosing device should be checked. If animals are to be treated collectively rather than individually, they should be grouped according to their bodyweight and dosed accordingly, in order to avoid under- or overdosing.
• Shake before use.

Contraindications: 

• Do not use in cases of known hypersensitivity to the active substances or to any of the excipient(s).
• Care should be taken to avoid the following practices because they increase the risk of development of resistance and could ultimately result in ineffective therapy:
• Too frequent and repeated use of anthelmintics from the same class, over an extended period of time.
• Underdosing, which may be due to underestimation of body weight, misadministration of the product, or lack of calibration of the dosing device (if any).
• Suspected clinical cases of resistance to anthelmintics should be further investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test).
• Where the results of the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to another pharmacological class and having a different mode of action should be used.
• Resistance to moxidectin has been reported mainly in Cooperia oncophora in some European countries. Resistance to other MLs in some strains of Cooperia spp. can imply concurrent resistance to Moxidectin. Resistance to triclabendazole has been reported in Fasciola hepatica in cattle in some European countries. Triclabendazole resistant F. hepatica hosted in sheep can be transferred to cattle grazing the same pasture. Therefore the use of this product should be based on local (regional, farm) epidemiological information about susceptibility of parasites, local history of treatments and recommendations on how to limit further selection for resistance to anthelmintics.
• This veterinary medicinal product should not be used for the treatment of single infections.
• It has been shown that rainfall immediately before or within 2 hours after treatment will not affect the efficacy of the product.
• The product is safe for use in pregnant and lactating animals.
• Signs of overdoses have not been seen at 5 times the recommended dose. However, if they do occur they should be consistent with the mode of action of moxidectin and would be manifested as transient salivation, depression, drowsiness and ataxia. Treatment is not generally necessary and recovery is generally complete within 24 to 48 hours. There is no specific antidote.
• Withdrawal Period: Meat and offal: 143 days.
• Milk: Do not use in cattle of any age intended to produce milk for human consumption.
• Due to the significant likelihood of cross-contamination of non-treated animals with this product due to grooming (licking), treated animals should be housed separately from non-treated animals throughout the withdrawal period. Non-compliance with this recommendation may lead to residues violations in non-treated animals.

Legal Category: POM-VPS.

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