MSD Ovipast Plus Suspension Injection For Sheep

Item: 148244

MPN: 812183

For the active immunisation of sheep as an aid in the control of pasteurellosis caused by M. haemolytica and P. trehalosi.

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Product Description

Uses:

For the active immunisation of sheep as an aid in the control of pasteurellosis caused by M. haemolytica and B. trehalosi. The vaccine maybe used as an aid in the control of pneumonic pasteurellosis in sheep of all ages from a minimum age of 3 weeks and in the control of systemic pasteurellosis in weaned fattening and breeding sheep. The vaccine may be used in pregnant ewes as an aid in the control of pasteurellosis in their lambs provided that the lambs receive sufficient immune colostrum during the first 1-2 days of life.
Onset of immunity: As with most inactivated vaccines, significant levels of immunity cannot be expected until 2 weeks after the second dose vaccine in the primary vaccination course.
Duration of immunity: Evidence of efficacy of the Pasteurella/Mannheimia component was generated in an experimental infection model using Heptavac P Plus and it is not possible to provide duration of immunity information using this system. There are reports that active immunity will last for up to 1 year and that passive immunity will persist for up to 4 weeks after birth in lambs from ewes vaccinated with conventional Pasteurella vaccines.

Dosage:

The vaccine should be administered by subcutaneous injection in the lateral side of the upper neck observing aseptic precautions. All sheep not previously vaccinated with this vaccine must receive two injections, each of 2.0 ml, separated by an interval of 4-6 weeks. Thereafter they must receive booster injections at intervals of not more than 12 months.
In adult breeding ewes these yearly booster injections should be given during the pre-lambing period, 4?6 weeks pre-lambing, as an aid in the control of pasteurellosis in their lambs.
On farms where the incidence of pasteurellosis is high, a supplementary booster vaccination with this vaccine may be required 2-3 weeks prior to expected seasonal outbreaks.
The vaccine bottle must be shaken well before use.
Strict precautions should be taken against contamination of the vaccine. The vaccine must be administered using a sterile needle and syringe, providing a fresh sterile needle is used each time the rubber cap is punctured, to avoid contamination of the remaining contents. Syringes and needles must be from gamma-irradiated packs or freshly sterilised by boiling for a least 20 minutes.
The use of an automatic vaccinator is recommended. Since the bottle is non-collapsible, a vaccinator with a vented draw-off spike or similar device must be used. The instructions supplied with such equipment should be noted and care should be taken to ensure the delivery of the full dose, particularly with the final few doses from the bottle.
Partially used containers must be discarded at the end of each day's operations, as re puncture of the rubber cap could cause contamination of the remaining contents.
This vaccine has been developed following research and development which resulted in the application of new ‘IRP’ technology for the manufacture of the Pasteurella/Mannheimia components in this vaccine. The inclusion of these IRP components should provide enhanced efficacy and cross protection e.g. protection against serotype A12, which is not included in the vaccine, has been demonstrated. Studies on the response of sheep to this vaccine show that two injections separated by an interval of 4-6 weeks are required to gain the full benefit of the ‘IRP’.

Contraindications:

Vaccinate healthy animals only.
The nutritional and metabolic status of pregnant ewes is extremely important at the time of vaccination. If in doubt, advice should be sought from a veterinary surgeon.
In any group of animals, a small number of individuals may fail to respond to vaccination as a result of immunological incompetence. Satisfactory immune responses will only be attained in healthy animals, thus it is important to avoid vaccination of animals which have intercurrent infection or metabolic disorder.
When handling sheep, stress should be avoided, particularly during the later stages of pregnancy when there is a risk of inducing metabolic disorders which may lead to abortion.
Can be used during pregnancy in ewes as an aid in the control of pasteurellosis in their lambs provided that the lambs receive sufficient immune colostrum during the first 1-2 days of life.
Withdrawal Period: Zero days.

Legal Category: POM-VPS.

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